Application process & FAQ
Translational Rheumatology Research - Postdoc position 80-100% at Center of Experimental Rheumatology
Immediately or by agreement
USZ Schlieren
The Center of Experimental Rheumatology (CER) at the University Hospital Zurich invites applications for a postdoctoral position within the ILD group, led by Prof. Anna-Maria Hoffmann-Vold. Be part of a translational project advancing ILD in rheumatic diseases. This role offers the opportunity to work at the intersection of molecular biology, translational research, and clinical innovation.
Your responsibilities
In this translational project, you will focus on identifying molecular mediators and mechanisms driving ILD progression in RMD. For this you will process lung samples using standard molecular biology techniques, but also novel techniques such as single nuclei (Sn)RNA-seq and spatial transcriptomics to generate a comprehensive molecular fingerprint. To further validate and assess prioritized molecular targets, functional and mechanistic studies will be conducted in 2D and 3D cell culture models, utilizing primary cells derived from both patients and healthy donors or precision cut slices. Additionally, you will perform large-scale bioinformatic analyses on datasets obtained from publicly available data. You will utilize state-of-the-art bioinformatic tools while also being encouraged to explore and implement novel, robust algorithms to enhance the analytical rigor of the study.
Your profile
- Ph.D. degree in Biomedical Sciences or related Life Science areas
- Strong expertise in cell culture and flow cytometry with proven ability to design and interpret in-vitro studies investigating molecular mechanisms
- Longstanding experience in cell culture and standard molecular biology techniques (FACS, Western blotting, qPCR, ELISA, etc.)
- Ability to work independently, high problem-solving skills and strong motivation to learn and establish new methods and protocols
- Passion for translational research, with the ability to independently navigate challenges and contribute innovative solutions
- You are creative, hardworking and a team player
- You are dedicated, highly motivated and enthusiastic for combining bioinformatic analysis and molecular biology methodology
- Entrepreneurial spirit
- Excellent communication (English) skills for an effective collaboration with all involved parties
- Eligibility to apply and obtain a visa for temporary residence is Switzerland
What we offer
- An interesting and varied job in an exciting and innovative organization
- Working in a highly committed team
- Access to an interdisciplinary research community
- Modern infrastructure
- The position is on 1-year contracts for a maximum of 3 years.
- Employment conditions which match the requirements and offer a high degree of flexibility
- Unique opportunity to co-develop a therapeutic for one of the most devastating condition
Who we are
The Center of Experimental Rheumatology (CER) of the University Hospital Zurich is a leading institute in Rheumatology research. The Center is one of the most renowned clinics in Switzerland, and has its laboratory at the Schlieren Campus, one of the most modern and attractive research centers in Switzerland, where researchers from the University and ETH Zurich, physicians, developers, and industry work together to alleviate the problems of patients with rheumatic diseases.
This postdoc position will focus on interstitial lung disease (ILD), a common and serious complication in individuals with systemic rheumatic musculoskeletal diseases (RMD). ILD significantly impacts patients morbidity and mortality. Currently, there are no therapies available that specifically modify the course of ILD in RMD pati
Place of work:
Center of Experimental Rheumatology, Wagistrasse 14, 8952 Schlieren
Any questions?
For further information please contact Prof. Dr. med. Anna-Maria Hoffmann-Vold, Head of Translational Research, Department of Rheumatology.
Benefits
On-site Day Care Center
On-site Day Care Center
Your child/children receive(s) loving care at our Day Care Center. Long opening hours, no vacation closure, and subsidized childcare places at five locations relieve the burden on working parents.
Health
Health
We help you to stay healthy. In addition to personal consultations and courses offered by Health Management, subsidized annual membership of ASVZ gives you access to more than 120 different sports.
Flexibility
Flexibility
We support a healthy work-life balance: almost half of our employees work part-time and 50% of work can be done from home, whenever their daily professional duties permit this.
Family friendliness
Family friendliness
Mothers are entitled to at least six months’ maternity leave (on their full salary for 16 weeks), and fathers are entitled to at least two months’ paternity leave (on their full salary for two weeks).
Further education & development
Further education & development
We accompany our employees throughout their professional career and support them in their development by offering them personalized career and further education opportunities.
Insurance
Insurance
We pay 60% of our employees’ pension fund contributions and can offer them special supplementary insurance conditions.
Mobility
Mobility
Our employees benefit from a discounted personal Zurich Transport Network (ZVV) annual travelcard or receive a fixed cash amount towards a GA Travelcard.
Telephony
Telephony
As a USZ employee, you and your family members benefit from special conditions for your private cell phone contract.
About USZ
The University Hospital of Zurich is one of the largest hospitals in Switzerland. Our more than 8,600 employees and around 700 trainees work every day for the well-being of our patients.
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